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Cardio-Oncology Mediterranean group
MEK inhibitors
(e.g., trametinib, cobimetinib, binimetinb, selumetinib)
Cardio-oncological evaluation*
before cancer treatment begins
Cardio-oncological evaluation* AND Home blood pressure monitoring
every 3 months for 1 year, then every 6 months during cancer treatment
* A cardio-oncological evaluation will systematically include at least one visit with blood pressure, blood glucose, lipid profile, GFR calculation, ECG and trans-thoracic echocardiography (TTE). Measurements of global longitudinal strain and 3D LVEF (if feasible) are recommended with the same machine.
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